The role of Nutrition and oxidative stress as aging factors in <i>Caenorhabditis elegans</i>

The molecular mechanism of aging, which has been a “black box” for many years, elucidated in recent and the nematode C. elegans, is model animal aging research, played major role its elucidation. From analysis elegans longevity-related mutant genes, signal transduction systems, with insulin/insulin-like growth factor system at core, have emerged. It become clear that this greatly affected by external nutrients involved downstream regulation oxidative stress, considered to be one main causes aging.